Profile
i-RNA Corporation is a Canadian preclinical biotech developing small interfering RNA (siRNA) therapeutics for diabetic retinopathy, a leading cause of global blindness. The company’s approach targets HOX transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA that regulates disease-driving pathways, including angiogenesis, inflammation, and oxidative stress, and key proteins including vascular endothelial growth factor (VEGF), enabling broader disease-modifying potential beyond current standards of care. Its modified siRNA molecules have demonstrated robust efficacy in preclinical models, including a lead candidate designed for topical delivery as an eye drop, offering a safer, patient-friendly alternative to intravitreal anti-VEGF injections and improving treatment accessibility and patient compliance.
Website
i-rna.caContact
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Ruby Zhao, Chief Operating Officer and CofounderTel: +1 343-336-6440Email: ruby.zhao@i-rna.ca
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